progesterone levels in pregnancy leading to miscarriage!!!!

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progesterone levels in pregnancy leading to miscarriage!!!!

Postby c12lar » Sun Oct 14, 2012 8:01 pm

Hi all miscarried 6 weeks ago at 6 weeks been doing lots of research into it all and i keep getting info on women with PCOS have more chance of having low levels of progesterone which can lead to miscarriage has anyone experienced this as this is the first i have heard of this all feed back appreciated :)
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Re: progesterone levels in pregnancy leading to miscarriage!

Postby Sazwell » Sun Oct 14, 2012 8:44 pm

Hi c12lar
Sorry to hear about your loss honey.. I find myself googling a lot, I sometimes drive myself crazy!!
I know very little on this honey but have read from posts on hear that their is no real evidence that this is true! We are as likely as someone without pcos! (I'm sure I've read this?? Could be wrong??) hope this helps honey?
Take care xxxx
Diagnosed PCOS 1998 - 2 rounds of clomid no o'v
150mg Clomid ov miracle BFP- Sept 08, Eptopic Oct 08
IVF #1March 09 BFN- short protocol IVF #2 long protocol BFP- 24/8/09 My miracle boy born 8/5/10- 2 blasts in the freezer!
May '12 FET 14.5.12 BFN 22.5.12
Awaiting next af to start Ivf #3 natural BFP 9.8.12 (shock????) no heartbeat mmc at 10weeks 21.9.12 x
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Re: progesterone levels in pregnancy leading to miscarriage!

Postby Doobykat » Fri Oct 26, 2012 9:07 am

Hi c12lar

Sorry to hear about your recent loss :(
I'm not sure that low levels of progesterone just affect women with PCOS, tbh. It really can happen to anyone, on any given cycle. I think the reason it pops up on internet searches being linked to PCOS is due to the amount of tracking of cycles & in early pregnancy that goes on in women with PCOS, due to the infertility treatments they receive.
I'm pretty sure that if all non PCOS women were monitored in the same way, the results wouldn't differ that much.
Although I've had two miscarriages, to my knowledge, neither have been due to low progesterone levels. They've both been "just one of those things" and likely due to genetic/chromosonal abnormalities.

Hope you're holding up ok post m/c. I know it can be a pretty traumatic time {{{hugs}}}

x x
MM/C Dec 2008 - 10w
MM/C Aug 2012 - 14w
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Re: progesterone levels in pregnancy leading to miscarriage!

Postby beaglelady » Fri Oct 26, 2012 9:53 pm

I disagree i do think there is a link i have had low progesterone every time i lost. Of course opinion differs but important convinced it didn't help
had the lot pcos endometriosis, adenomyosis and fibroids. now in early surgical menopause.
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Re: progesterone levels in pregnancy leading to miscarriage!

Postby c12lar » Fri Nov 02, 2012 8:34 pm

thanks very much for your posts ladies it helps hugely to hear everyone's thoughts on this shows me im not being silly googling things and trying to find a reason for M/C, i have spoke to doctors etc and they wont look into anything until we have M/C 3 times which i think is utter shocking when if it was low prog a simple blood test could possibly save pregnancy.
My next mission is to get my weight down a bit as since M/C i feel swollen and bloated etc (been on the peppermint tea) so something to keep me occupied for the mean time and ladies you never know its sometimes true when your not thinking about it too much that's when its likely to happen.

Fingers x for you all and good luck xxxx
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Re: progesterone levels in pregnancy leading to miscarriage!

Postby espoir » Tue Nov 06, 2012 7:59 pm

Sorry to hear of your loss. I've been googling a lot as well as really struggling 2nd time round to sustain a pregnancy! I am routinely prescribed progesterone during the 2ww, and it hasn't prevented either of my miscarriages (chemical and MMC). Of course it's always possible that low progesterone would cause a miscarriage, but I'm not sure it would be specific to ladies with PCOS nor how common it is. Have you ever had your progesterone levels checked as part of screening for ovulation? Probably having a luteal phase defect would also indicate progesterone issues. Have you had your thyroid levels checked, as this is a frequent cause of MC. Unfortunately MC is quite common (my GP said 1:3) - I have been surprised by how many people have had one - but most likely the pregnancy failed because of genetic/chromosomal issues and next time round you will have a healthy pregnancy.
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Re: progesterone levels in pregnancy leading to miscarriage!

Postby Amber » Thu Nov 29, 2012 6:10 pm

The main thing I have experienced with low progesterone levels is in the form of a luteal phase defect. However low progesterone was not the cause of miscarriage. From my own research, progesterone can be converted into cortisol in times of stress. If the stress is chronic this can lead to problems like luteal phase defects. Progesterone is also made from cholesterol in the body (i.e. cholesterol is not dangerous to consume and is actually a healthy nutrient!). I managed to correct my luteal phase defect by tackling stress and consuming more animal fats in the diet.
Diagnosed March 09
Lap & Dye Aug 09
6 x Clomid 50mg Ov BFN - 24-26 days
1 x clomid 100mg over stimulated
IVF 1st round - 2 blasts BFN
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